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Better lab animal models for translational neuroscience research and CNS drug development

Lab Animal volume 46, pages 91–92 (2017)Cite this article

To the editor

Although the importance of animal models in preclinical research and drug discovery is widely recognized, there are multiple limitations and potential problems in this field1,2. For example, recent analyses of mouse models of amyotrophic lateral sclerosis (ALS) have illustrated the gap between phenotype and the “real” human disorder we attempt to model1.

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Authors and Affiliations

  1. Institute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russia

    Darya A Meshalkina

  2. Research Institute of Marine Drugs and Nutrition, Guangdong Ocean University, Zhanjiang, China

    Cai Song & Allan V Kalueff

  3. ZENEREI Institute and the International Zebrafish Neuroscience Research Consortium (ZNRC), Slidell, Louisiana, USA

    Allan V Kalueff

  4. Institute of Chemical Technologies, Ural Federal University, Yekaterinburg, Russia

    Allan V Kalueff

  5. Laboratory of Biological Psychiatry, St. Petersburg State University, St. Petersburg, Russia

    Allan V Kalueff

Authors
  1. Darya A Meshalkina
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  2. Cai Song
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  3. Allan V Kalueff
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Corresponding author

Correspondence to Allan V Kalueff.

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The authors declare no competing financial interests.

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Meshalkina, D., Song, C. & Kalueff, A. Better lab animal models for translational neuroscience research and CNS drug development. Lab Anim 46, 91–92 (2017). https://doi.org/10.1038/laban.1236

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